Alzheimer's Research News

June 20, 2025

Top Headlines

Microscopic Heist: How Lung Bacteria Forge Weapons to Steal Iron and Survive

June 19, 2025 — Researchers investigating the enigmatic and antibiotic-resistant Pandoraea bacteria have uncovered a surprising twist: these pathogens don't just pose risks they also produce powerful natural ...

Hidden in Your Dna: The Mutation Combo That Raises Clot Risk by 180%

June 8, 2025 — Genetic research in Sweden has unveiled three new gene variants that dramatically increase the risk of venous blood clots, sometimes by up to 180%. These discoveries build on existing knowledge of Factor V Leiden and suggest that genetics plays a ...

Immune System Discovery Reveals Potential Solution to Alzheimer's

June 2, 2025 — A new way of thinking about Alzheimer's disease has yielded a discovery that could be the key to stopping the cognitive decline seen in Alzheimer's and other neurodegenerative diseases, including ALS and ...

Common Gene Variant Doubles Dementia Risk for Men

May 30, 2025 — New research has found that men who carry a common genetic variant are twice as likely to develop dementia in their lifetime compared to ...

Research Untangles Role of Stress Granules in Neurodegenerative Disease

May 28, 2025 — Scientists found that stabilizing stress granules suppresses the effects of ALS-causing mutations, correcting previous models that imply stress granules promote amyloid ...

Whether It's Smoking or Edibles, Marijuana Can Be Bad for Your Heart, Study Suggests

May 28, 2025 — A new study finds that chronic cannabis use -- whether it's smoked or consumed in edible form -- is associated with significant cardiovascular ...

First Vascularized Model of Stem Cell Islet Cells

May 23, 2025 — Researchers have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance promises to improve diabetes research and cell-based ...

Survival Trick: Pathogen Taps Iron Source in Immune Cells

May 19, 2025 — The body defends itself against pathogens by depriving them of vital iron. However, this strategy doesn't always succeed against Salmonella. Researchers have discovered that these bacteria specifically target iron-rich regions within immune cells to ...

Study Reveals Impacts of Alzheimer's Disease on the Whole Body

May 17, 2025 — While Alzheimer's disease is mostly considered a disorder of the brain, emerging evidence suggests that the condition also affects other organs of the body. Working with the laboratory fruit fly, researchers provide a new understanding of how ...

Sugar-Coated Nanotherapy Dramatically Improves Neuron Survival in Alzheimer's Model

May 14, 2025 — In many neurodegenerative diseases, proteins misfold and clump together in brain tissue. Scientists developed a new therapy made of peptides and a sugar that naturally occurs in plants. The ...

Knowing Your Alzheimer's Risk May Ease Anxiety but Reduce Motivation for Healthy Habits

May 7, 2025 — Learning about one's risk for Alzheimer's disease may not lead to emotional distress, but motivation to maintain healthy lifestyle changes tends to fade over time, even in people at high risk, ...

Most People Say They Want to Know Their Risk for Alzheimer's Dementia, Fewer Follow Through

May 6, 2025 — A new study examines the choices healthy research volunteers make when given the opportunity to learn their risk of developing Alzheimer's disease dementia. The researchers found a large discrepancy ...

Latest Headlines

updated 10:18am EDT

Low Iron Could Cause Brain Fog During Menopause Transition

Apr. 30, 2025 — New research sheds light on an understudied area of science: iron levels in the blood and their relationship to cognitive performance in women transitioning into menopause. The findings are good news ...

First Synthetic 'Mini Prion' Shows How Protein Misfolding Multiplies

Apr. 30, 2025 — Prions transmit their abnormally folded shape onto other proteins. Researchers designed a synthetic fragment of the tau protein that exhibits prion-like behavior. Misfolded tau proteins are the ...

Increasing Physical Activity in Middle Age May Protect Against Alzheimer's Disease

Apr. 30, 2025 — An increase in physical activity between the ages of 45 and 65 could help prevent Alzheimer's disease, while inactivity may be detrimental to brain ...

AI Helps Unravel a Cause of Alzheimer's Disease and Identify a Therapeutic Candidate

Apr. 25, 2025 — A new study found that a gene recently recognized as a biomarker for Alzheimer's disease is actually a cause of it, due to its previously unknown ...

Immune Cells Drive Congenital Paralysis Disease

Apr. 25, 2025 — Patients with spastic paraplegia type 15 develop movement disorders during adolescence that may ultimately require the use of a wheelchair. In the early stages of this rare hereditary disease the ...

Engineered Microglia Show Promise for Treating Alzheimer's and Other Brain Diseases

Apr. 21, 2025 — A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer's disease and other neurological ...

Hereditary Alzheimer's: Blood Marker for Defective Neuronal Connections Rises Early

Apr. 16, 2025 — Individuals with a genetic predisposition to Alzheimer's disease show altered blood levels indicating damaged neuronal contacts as early as 11 years ...

Researchers Identify a Novel Mechanism of Fetal Anemia Linked to Mitochondrial Protein Synthesis Deficiency

Apr. 10, 2025 — A team of researchers has uncovered a previously unrecognized role of mitochondrial protein synthesis in the maintenance of intracellular iron ...

Advanced Imaging Reveals Mechanisms That Cause Autoimmune Disease

Apr. 9, 2025 — Those who suffer myasthenia gravis experience muscle weakness that can affect the muscles we use to blink, smile and move our bodies. Researchers used a cutting-edge imaging technique to uncover new ...

ALS Drug Effectively Treats Alzheimer's Disease in New Animal Study

Apr. 8, 2025 — Experimental drug NU-9 -- a small molecule compound approved by the U.S. Food and Drug Administration (FDA) for clinical trials for the treatment of amyotrophic lateral sclerosis (ALS) -- improves ...

Study Strengthens Link Between Shingles Vaccine and Lower Dementia Risk

Apr. 2, 2025 — A new analysis of a vaccination program in Wales found that the shingles vaccine appeared to lower new dementia diagnoses by 20% -- more than any other known ...

Highly Accurate Blood Test Diagnoses Alzheimer's Disease, Measures Extent of Dementia

Mar. 31, 2025 — A newly developed blood test for Alzheimer's disease not only aids in the diagnosis of the neurodegenerative condition but also indicates how far it has progressed, according to a new ...

Digital Technology and AI Can Support Workers With Dementia

Mar. 27, 2025 — People with dementia can enjoy productive and rewarding working lives in the digital era, contrary to the widespread stereotype that dementia is incompatible with the use of modern technology, ...

AI Is as Good as Pathologists at Diagnosing Celiac Disease, Study Finds

Mar. 27, 2025 — A machine learning algorithm was able to correctly identify in 97 cases out of 100 whether or not an individual had Celiac disease based on their biopsy, new research has shown. The AI tool, which ...

ADHD May Be Associated With an Increased Risk of Dementia

Mar. 25, 2025 — An adult brain affected by attention deficit disorder with or without hyperactivity (ADHD) presents modifications similar to those observed in individuals suffering from dementia. These are the ...

Study Confirms Accuracy of Blood Test for Early Alzheimer's Detection in Asian Populations

Mar. 24, 2025 — A study has demonstrated the high accuracy of plasma p-tau217 as a blood-based biomarker for detecting abnormal brain beta-amyloid pathology, a hallmark of Alzheimer's ...

Anti-Amyloid Drug Shows Signs of Preventing Alzheimer's Dementia

Mar. 19, 2025 — An experimental drug appears to reduce the risk of Alzheimer's-related dementia in people destined to develop the disease in their 30s, 40s or 50s, according to the results of a new study. The ...

Inflammatory Messenger Fuels Alzheimer's

Mar. 17, 2025 — Researchers have detailed the precise mechanism through which the inflammatory signaling molecule IL-12 contributes to Alzheimer's ...

Cause of Post-COVID Inflammatory Shock in Children Identified

Mar. 12, 2025 — MIS-C is a serious inflammatory shock that affects children. It can occur several weeks after a COVID infection and can be life-threatening. Until now, however, the precise cause of the condition was ...

Compound Found in Common Herbs Inspires Potential Anti-Inflammatory Drug for Alzheimer's Disease

Mar. 10, 2025 — The herb rosemary has long been linked with memory: 'There's rosemary, that's for remembrance,' says Ophelia in Shakespeare's Hamlet. So it is fitting that researchers would ...

Alzheimer's Treatment May Lie in the Brain's Own Cleanup Crew

Mar. 6, 2025 — A new study suggests a promising alternative to previous attempts to remove the sticky, toxic amyloid beta plaques from brains with Alzheimer's Disease: enhancing the brain's own immune ...

Novel Enzyme Found in Gut Bacteria Could Revolutionize Prebiotic Research

Mar. 6, 2025 — Certain glycans -- sugar-like compounds with carbohydrate chains -- containing galactose, may exhibit potential prebiotic properties that support human health. Identifying enzymes capable of breaking ...

Researchers Identify Molecular Glues That Protect Insulin-Producing Cells from Damage Related to Diabetes

Mar. 4, 2025 — Researchers have discovered a novel approach to protecting insulin-producing beta cells from the damaging effects of glucolipotoxicity - a harmful condition linked to the progression of type 2 ...

Nuns Contribute 30 Years of Critical Insight Into Dementia Disorders

Feb. 26, 2025 — Researchers published a study analyzing more than 30 years of aging and dementia patterns of 678 ...

Atherosclerosis: How Immune Cells Migrate Into Plaques

Feb. 25, 2025 — CD8+ T cells accumulate in atherosclerotic plaques. Researchers identify a crucial signaling pathway -- with therapeutic ...

Small Amounts of Moderate to Vigorous Physical Activity Are Associated With Big Reductions in Dementia Risk

Feb. 20, 2025 — A little movement could help prevent dementia, even for frail older adults, suggests a new ...

New Molecular Mechanisms Linked to Insulin Resistance

Feb. 19, 2025 — Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide. In affected people, insulin is unable to ...

Peristaltic Pump Flow Induces Amyloid Formation

Feb. 28, 2025 — Researchers found that peristaltic pump flow mechanically breaks supersaturation to induce amyloid formation by hen egg white lysozyme, a-synuclein, amyloid b 1-40, and b2-microglobulin. The high ...

Mouse Study Finds Impaired Cell Development: Intermittent Fasting Could Be Unsafe for Teenagers

Feb. 14, 2025 — A recent study reveals that age plays a significant role in the outcomes of intermittent fasting. Researchers discovered that chronic intermittent fasting disrupted the development of ...

Cancer's Ripple Effect May Promote Blood Clot Formation in the Lungs

Feb. 11, 2025 — Blood clots form in response to signals from the lungs of cancer patients -- not from other organ sites, as previously thought -- according to a preclinical study. Clots are the second-leading cause ...